Muscle Shoals is a medium-sized city located in the state of Alabama. With a population of 17,019 people and five associated neighborhoods, Muscle Shoals is the 41st largest community in Alabama.

A relatively large number of people in Muscle Shoals telecommute to their jobs. Overall, about 9.42% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Being a small city, Muscle Shoals does not have a public transit system used by locals to get to and from work.

The education level of Muscle Shoals citizens is a little higher than the average for US cities and towns: 21.19% of adults in Muscle Shoals have at least a bachelor's degree.

The per capita income in Muscle Shoals in 2022 was $35,791, which is wealthy relative to Alabama, and upper middle income relative to the rest of the US. This equates to an annual income of $143,164 for a family of four. However, Muscle Shoals contains both very wealthy and poor people as well.

Muscle Shoals is a very ethnically-diverse city. The people who call Muscle Shoals home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Muscle Shoals residents report their race to be White, followed by Black or African-American. Important ancestries of people in Muscle Shoals include English, Irish, German, Italian, and European.

The most common language spoken in Muscle Shoals is English. Other important languages spoken here include Spanish and Langs. of India.