Santee is a larger medium-sized city located in the state of California. With a population of 59,051 people and 16 associated neighborhoods, Santee is the 156th largest community in California.

Housing costs in Santee are among some of the highest in the nation, although real estate prices here don't compare to real estate prices in the most expensive communities in California.

Also of interest is that Santee has more people living here who work in computers and math than 95% of the places in the US.

Telecommuters are a relatively large percentage of the workforce: 11.92% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

The overall education level of Santee citizens is substantially higher than the typical US community, as 31.87% of adults in Santee have at least a bachelor's degree, and the average American community has 21.84%.

The per capita income in Santee in 2022 was $42,749, which is middle income relative to California, and upper middle income relative to the rest of the US. This equates to an annual income of $170,996 for a family of four. However, Santee contains both very wealthy and poor people as well.

Santee is an extremely ethnically-diverse city. The people who call Santee home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Santee residents report their race to be White, followed by Asian. Santee also has a sizeable Hispanic population (people of Hispanic origin can be of any race). People of Hispanic or Latino origin account for 19.65% of the city’s residents. Important ancestries of people in Santee include German, English, Irish, Italian, and European.

The most common language spoken in Santee is English. Other important languages spoken here include Spanish and Arabic.