Macclenny is a somewhat small city located in the state of Florida. With a population of 8,178 people and two associated neighborhoods, Macclenny is the 242nd largest community in Florida. Macclenny has seen a significant amount of newer housing growth in recent years. Quite often, new home construction is the result of new residents moving in who are middle class or wealthier, attracted by jobs, a healthy local economy, or other amenities as they leave nearby or far away areas for greener pastures. This seems to be the case in Macclenny, where the median household income is $73,942.00.

One interesting thing about the economy is that relatively large numbers of people worked from their home: 9.50% of the workforce. While this number may seem small overall, as a fraction of the total workforce this is high compared to the rest of the county. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Being a small city, Macclenny does not have a public transit system used by locals to get to and from work.

In terms of college education, Macclenny is nearly on par with the US average for all cities of 21.84%: 20.87% of adults 25 and older in Macclenny have a bachelor's degree or advanced degree.

The per capita income in Macclenny in 2022 was $33,618, which is lower middle income relative to Florida, and middle income relative to the rest of the US. This equates to an annual income of $134,472 for a family of four. However, Macclenny contains both very wealthy and poor people as well.

Macclenny is an extremely ethnically-diverse city. The people who call Macclenny home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Macclenny residents report their race to be White, followed by Black or African-American. Important ancestries of people in Macclenny include Irish, English, German, French, and Polish.

The most common language spoken in Macclenny is English. Other important languages spoken here include Spanish and Greek.