Cherokee is a somewhat small city located in the state of Iowa. With a population of 5,186 people and two associated neighborhoods, Cherokee is the 90th largest community in Iowa.

A relatively large number of people in Cherokee telecommute to their jobs. Overall, about 8.54% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Compared to the rest of the country, citizens of Cherokee spend much less time in their cars: on average, their commute to work is only 14.67 minutes. This also means that noise and pollution levels in the city are less than they would otherwise be.

The citizens of Cherokee are slightly better educated than the national average of 21.84% for all cities and towns, with 24.58% of adults in Cherokee having a bachelor's degree or advanced degree.

The per capita income in Cherokee in 2022 was $38,225, which is middle income relative to Iowa, and upper middle income relative to the rest of the US. This equates to an annual income of $152,900 for a family of four. However, Cherokee contains both very wealthy and poor people as well.

Cherokee is a somewhat ethnically-diverse city. The people who call Cherokee home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Cherokee residents report their race to be White, followed by Asian. Important ancestries of people in Cherokee include German, Irish, English, Czech, and Swedish.

The most common language spoken in Cherokee is English. Other important languages spoken here include Spanish and Polish.