Cherokee is a somewhat small city located in the state of Iowa. With a population of 5,186 people and two associated neighborhoods, Cherokee is the 90th largest community in Iowa.

Telecommuters are a relatively large percentage of the workforce: 8.54% of people work from home. While this number may seem small overall, as a fraction of the total workforce it is high relative to the nation. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Residents of the city have the good fortune of having one of the shortest daily commutes compared to the rest of the country. On average, they spend only 14.67 minutes getting to work every day.

The citizens of Cherokee are slightly better educated than the national average of 21.84% for all cities and towns, with 24.58% of adults in Cherokee having a bachelor's degree or advanced degree.

The per capita income in Cherokee in 2022 was $38,225, which is middle income relative to Iowa, and upper middle income relative to the rest of the US. This equates to an annual income of $152,900 for a family of four. However, Cherokee contains both very wealthy and poor people as well.

Cherokee is a somewhat ethnically-diverse city. The people who call Cherokee home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Cherokee residents report their race to be White, followed by Asian. Important ancestries of people in Cherokee include German, Irish, English, Czech, and Swedish.

The most common language spoken in Cherokee is English. Other important languages spoken here include Spanish and Polish.