Maquoketa is a somewhat small city located in the state of Iowa. With a population of 6,051 people and two associated neighborhoods, Maquoketa is the 66th largest community in Iowa.

A relatively large number of people in Maquoketa telecommute to their jobs. Overall, about 8.89% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Being a small city, Maquoketa does not have a public transit system used by locals to get to and from work.

The education level of Maquoketa citizens, measured as those with bachelor's degrees or advanced degrees, is similar to the national average for all American cities and towns. 17.04% of adults 25 and older in Maquoketa have a college degree.

The per capita income in Maquoketa in 2022 was $33,246, which is lower middle income relative to Iowa, and middle income relative to the rest of the US. This equates to an annual income of $132,984 for a family of four. However, Maquoketa contains both very wealthy and poor people as well.

The people who call Maquoketa home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Maquoketa residents report their race to be White, followed by Black or African-American. Important ancestries of people in Maquoketa include German, Irish, English, Polish, and Swedish.

The most common language spoken in Maquoketa is English. Other important languages spoken here include Italian and Spanish.