Potosi is a very small city located in the state of Missouri. With a population of 2,549 people and two associated neighborhoods, Potosi is the 239th largest community in Missouri.

Potosi is a small city, and as such doesn't have a public transit system that people use to get to and from their jobs every day.

In Potosi, just 9.01% of people over 25 hold a college degree, which is very low compared to the rest of the nation, whereas the average among all cities is 21.84%.

The per capita income in Potosi in 2022 was $22,651, which is low income relative to Missouri and the nation. This equates to an annual income of $90,604 for a family of four. However, Potosi contains both very wealthy and poor people as well.

Potosi is a somewhat ethnically-diverse city. The people who call Potosi home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Potosi residents report their race to be White, followed by Black or African-American. Important ancestries of people in Potosi include German, English, Irish, French, and Scots-Irish.

The most common language spoken in Potosi is English. Other important languages spoken here include French and Polish.