Greenville is a somewhat small borough located in the state of Pennsylvania. With a population of 5,459 people and four associated neighborhoods, Greenville is the 267th largest community in Pennsylvania. Much of the housing stock in Greenville was built prior to World War II, making it one of the older and more historic boroughs in the country.

A relatively large number of people in Greenville telecommute to their jobs. Overall, about 8.37% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Because there are quite a few people attending college in Greenville, it is thought of as a college town. To the benefit of the many students in the area, Greenville provides a number of services, amenities and opportunities geared towards their needs and activities.

The education level of Greenville citizens is substantially higher than the typical US community, as 29.06% of adults in Greenville have at least a bachelor's degree.

The per capita income in Greenville in 2022 was $27,370, which is low income relative to Pennsylvania, and lower middle income relative to the rest of the US. This equates to an annual income of $109,480 for a family of four. However, Greenville contains both very wealthy and poor people as well.

The people who call Greenville home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Greenville residents report their race to be White, followed by Black or African-American. Important ancestries of people in Greenville include German, Irish, Italian, English, and Polish.

The most common language spoken in Greenville is English. Other important languages spoken here include Spanish and French.