Waynesburg is a very small borough located in the state of Pennsylvania. With a population of 3,701 people and three associated neighborhoods, Waynesburg is the 388th largest community in Pennsylvania. Waynesburg has an unusually large stock of pre-World War II architecture, making it one of the older and more historic boroughs.

Also of interest is that Waynesburg has more people living here who work in computers and math than 95% of the places in the US.

A relatively large number of people in Waynesburg telecommute to their jobs. Overall, about 7.94% of the workforce works from home. While this may seem like a small number, as a fraction of the total workforce it ranks among the highest in the country. These workers are often telecommuters who work in knowledge-based, white-collar professions. For example, Silicon Valley has large numbers of people who telecommute. Other at-home workers may be self-employed people who operate small businesses out of their homes.

Waynesburg is a small town with a large college student population. Because of this, there is a real youthful, hip vibe to the place, and much of the life in the town is centered on the college. This has helped Waynesburg to buck the trend of other small towns that have suffered declining populations over the past 20 to 30 years. Spending by students, and faculty and staff jobs, are a big part of the local economy.

Being a small borough, Waynesburg does not have a public transit system used by locals to get to and from work.

The overall education level of Waynesburg citizens is substantially higher than the typical US community, as 33.28% of adults in Waynesburg have at least a bachelor's degree, and the average American community has 21.84%.

The per capita income in Waynesburg in 2022 was $29,950, which is lower middle income relative to Pennsylvania and the nation. This equates to an annual income of $119,800 for a family of four. However, Waynesburg contains both very wealthy and poor people as well.

The people who call Waynesburg home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Waynesburg residents report their race to be White, followed by Black or African-American. Important ancestries of people in Waynesburg include German, Italian, English, Irish, and Slovak.

The most common language spoken in Waynesburg is English. Other important languages spoken here include Polish and German/Yiddish.